Csicsvari Group
Systems Neuroscience
Memory formation is crucial for learning new facts and skills. This process of encoding, storing, and ultimately recalling memories involves complex interactions between various brain regions and neurons in embedded circuits that form complex code to encode these memory traces. The Csicsvari group studies how learning is implemented in the brain.
During learning, new memories are acquired and subsequently consolidated to ensure their successful later recall. The Csicsvari group focuses on understanding how learning leads to memory formation in neuronal circuits by investigating the neuronal system mechanisms of memory formation and stabilization. They also investigate the mnemonic role of neuronal populations and their interactions in brain areas involved in spatial memory processing. The group seeks to understand how neuronal circuits process information and form spatial memories by recording the activity of many neurons in different brain regions during spatial learning tasks and sleep. In their research, the group uses optogenetic methods to selectively manipulate neuronal activity in different brain areas.
Group Leader
Administrative Support
Team
Current Projects
Oscillatory interactions in working memory | Role of hippocampal formation in spatial learning | Activation of brain structures using light sensitive channels to study memory formation
Publications
Bollmann L. 2024. Stability and change in the memory system during rest. Institute of Science and Technology Austria. View
Ku SP, Atucha E, Alavi N, Mulla-Osman H, Kayumova R, Yoshida M, Csicsvari JL, Sauvage MM. 2024. Phase locking of hippocampal CA3 neurons to distal CA1 theta oscillations selectively predicts memory performance. Cell Reports. 43(6), 114276. View
Rangel Guerrero DK, Balueva K, Barayeu U, Baracskay P, Gridchyn I, Nardin M, Roth CN, Wulff P, Csicsvari JL. 2024. Hippocampal cholecystokinin-expressing interneurons regulate temporal coding and contextual learning. Neuron. View
Chiossi HSC. 2024. Adaptive hierarchical representations in the hippocampus. Institute of Science and Technology Austria. View
Nardin M, Csicsvari JL, Tkačik G, Savin C. 2023. The structure of hippocampal CA1 interactions optimizes spatial coding across experience. The Journal of Neuroscience. 43(48), 8140–8156. View
ReX-Link: Jozsef Csicsvari
Career
Since 2011 Professor, Institute of Science and Technology Austria (ISTA)
2008 – 2011 MRC Senior Scientist (tenured), MRC Anatomical Neuropharmacology Unit, University of Oxford, UK
2003 – 2008 MRC Senior Scientist (tenure-track), MRC Anatomical Neuropharmacology Unit, University of Oxford, UK
2001 – 2002 Research Associate, Center for Behavioral and Molecular Neuroscience, Rutgers University, New Brunswick, USA
1999 – 2001 Postdoctoral Fellow, Center for Behavioral and Molecular Neuroscience, Rutgers University, New Brunswick, USA
1999 PhD, Rutgers University, New Brunswick, USA
Selected Distinctions
2011 ERC Starting Grant
2010 Title of Ad Hominem Professor in Neuroscience at the University of Oxford
