16. Feb 2026

Cellular Logistics: Membrane Trafficking and Signaling in Health and Disease

Datum: 16. February 2026 | 11:30 – 12:30
Sprecher: Marta Miaczynska, International Institute of Molecular and Cell Biology
Veranstaltungsort: Raiffeisen Lecture Hall
Sprache: Englisch

Endocytic pathways mediate uptake of extracellular cargo and critically regulate receptors for growth factors and cytokines to maintain proper control of cell proliferation, survival, and differentiation. Dysregulation of endosomal trafficking and the ESCRT machinery affects inflammatory responses, lysosome biogenesis, and metabolic homeostasis, creating vulnerabilities relevant for cancer therapy. Work on signaling endosomes and macropinocytic uptake driven by oncogenic receptor tyrosine kinases such as AXL underscores the role of endocytic regulation in tumor progression, metastasis, and precision medicine–oriented interventions.

Prof. Miczyska will willingly meet (if they are available): Carrie Bernecky; Carl-Phillip Heisenberg; Martin Hetzer; Andela Saric; and Michael Sixt. In addition, she is open to any other scientists who will be eager to talk to her